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  • Improve DM through root cause analysis

    Root cause analysis, long a popular tool for quality improvement initiatives, holds tremendous promise for occupational health professionals seeking to improve their disability management programs, says Jennifer Christian,MD, president and chief medical officer of Webility Corp. in Wayland, MA.
  • It’s safety first for a growing number of occ-health nurses, say observers

    Mirroring an overall trend in health care quality, employee safety increasingly is taking center stage for occupational health nurses, say the experts. And this trend is growing in two parallel directions: an expanding role for current occ-health nursing positions, as well as potential new job opportunities.
  • High-Dose Imatinib Mesylate (Gleevec®) for CML

    Imatinib was administered to newly diagnosed patients with chronic-phase myelogenous leukemia at a dose (800 mg daily) double what is commonly prescribed. Cytogenetic and molecular responses were significantly better than observed in an historical cohort of similar patients treated with 400 mg daily.
  • Phase II Data on Cetuximab (Erbitux™)

    In a phase II trial of cetuximab (Erbitux) given once weekly to patients with advanced colorectal cancer who had failed prior irinotecan treatment, a modest response rate was observed and the toxicity profile was shown to be manageable.
  • The Value of Post Adjuvant Chemotherapy Screening in Colorectal Cancer Patients

    In an analysis of important clinical outcomes after adjuvant chemotherapy for stage II and III colorectal cancer, Chau and colleagues from the United Kingdom reviewed the experiences of 530 patients. Of these, 154 relapsed with metastatic disease, local recurrence, or metachronous tumor.
  • Noninvasive Ventilation in Hypoxemic Respiratory Failure

    Noninvasive positive-pressure ventilation (NPPV) was assessed in 105 patients with severe acute hypoxemic respiratory failure. The use of noninvasive positive pressure ventilation (NPPV) is effective to reduce intubation and mortality in patients with acute hypoxemic respiratory failure.
  • Predicting Outcome in Pulmonary Embolism Using CT Angiography

    No CT variables predicted severe in-hospital morbidity and mortality (death from pulmonary embolism, death from any cause, or cardiac arrest) in patients with PE. However, ventricular septal bowing and increased RV/LV diameter ratio were both strongly predictive of less severe morbidity, namely, subsequent ICU admission, and oligemia was associated with subsequent intubation and vasopressor use.
  • Leapfrog and Critical Care: Evidence and Reality in the ICU

    Leapfrog Groups standards for critical care are not grounded sufficiently in evidence to mandate their stringent and universal implementation. Rather, most of the guidelines are grounded in common sense and rational extrapolation of the data. As such, they are a reasonable starting point for debate by physicians and policymakers about optimal methods of achieving intensivist-guided care of critically ill patients.
  • Clinical Briefs in Primary Care

  • More from the Women’s Health Initiative

    The latest news from the womens health initiative (WHI) includes 3 noteworthy reports: the news release announcing the cancellation of the estrogen-only arm of the clinical trial,1 a comparison of the participants in the 2 clinical trial arms(estrogen-progestin and estrogen-only),2 and the updated, adjudicated lorectal cancer results from the estrogen-progestin arm.3